Hydroquinone diethers, their preparation and their use

ABSTRACT

Hydroquinone diethers of the general formula I    &lt;IMAGE&gt;  I  where R1 is hydrogen, halogen or C1-C6-alkyl, A and B are each unsubstituted or substituted methylene, ethylene or propylene and X and Y are each unsubstituted or substituted hetaryl, processes for their preparation and pesticides.

This application is a continuation of application Ser. No. 681,256,filed on Apr. 8, 1991, now abandoned.

The present invention relates to hydroquinone diethers of the formula I##STR2## where R¹ is hydrogen, halogen or C₁ -C₆ -alkyl,

A and B are each methylene, ethylene or propylene, where these groupsmay carry one or two C₁ -C₃ -alkyl radicals, and

X and Y are each a 5-membered heteroaromatic structure containing, inaddition to carbon atoms, from 1 to 3 hetero atoms from the groupconsisting of nitrogen, oxygen and sulfur, which may carry from one tothree of the following groups: halogen, C₁ -C₆ -alkyl, C₁ -C₄-haloalkyl, C₁ -C₆ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄-alkyl, C₃ -C₈ -cycloalkyl, C₂ -C₈ -alkenyl, aryl or aryl-C₁ -C₁₀-alkyl, where these aromatic radicals in turn may carry from one to fivehalogen atoms and from one to three of the following groups: C₁ -C₄-alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy or C₁ -C₄-alkylthio.

The present invention furthermore relates to a process for thepreparation of the compounds I and pesticides which contain thecompounds I.

The literature discloses 4-aryloxyphenol hetaryl methyl ethers (EP-A239,047, EP-A 287,959, EP-A 289,919, EP-A 353,571 and EP-A 353,674)having insecticidal activity.

It is an object of the present invention to provide novel hydroquinonediethers having improved insecticidal properties.

We have found that this object is achieved by the hydroquinone diethersof the formula I which are defined at the outset and a process for theirpreparation. We have also found pesticides and methods for controllingpests with these agents.

The hydroquinone diethers of the formula I can be prepared by variousmethods. They are obtained, for example, by the following process:

A 4-hydroxyphenol ether of the general formula II is etherified in aconventional manner in an inert organic solvent in the presence of abase with a heterarylalkyl derivative of the formula IIIa or IIIb, theresulting diether derivative IVa or IVb is converted in a conventionalmanner, by eliminating the protective group R, into the correspondingmonoether Va or Vb, which is then etherified in a conventional mannerwith a heterarylalkyl derivative IIIa or IIIb to give I.

The reaction steps are shown in the scheme below: ##STR3##

In formula II, R is a protective group which is inert under the reactionconditions, such as straight-chain or branched C₁ -C₆ -alkyl, e.g.tert-butyl, benzyl or silyl which is trisubstituted by C₁ -C₄ -alkyl oraryl, e.g. trimethylsilyl, tert-butyldimethylsilyl, phenyldimethylsilylor tert-butyldiphenylsilyl, in particular tertbutyldimethylsilyl.

In formulae IIIa and IIIb, Z is a nucleofugic leaving group, for examplea sulfonyl radical, such as methylsulfonyl, trifluoromethylsulfonyl,phenylsulfonyl or p-tolylsulfonyl, halogen, such as chlorine, bromine oriodine, in particular chlorine or bromine.

The etherification reactions of II with IIIa or IIIb (1st stage) or ofVa or Vb with IIIb or IIIa (3rd stage) are generally carried out in aninert organic solvent in the presence of a base at from -50° to 150° C.,in particular from -20° to 120° C.

The reactions usually take place at a sufficient rate at above -20° C.In general, there is no need to exceed 120° C. Since the reactions takeplace with evolution of heat in some cases, it may be advantageous toprovide a means of cooling.

Examples of suitable solvents are hydrocarbons, such as pentane, hexane,benzene, toluene and xylenes, halohydrocarbons, such as methylenechloride, ethylene chloride, chloroform or chlorobenzene, ethers, suchas diethyl ether, di-n-butyl ether, methyl tert-butyl ether,tetrahydrofuran or dioxane, ketones, such as acetone or methyl ethylketone, nitriles, such as acetonitrile, alcohols, such as methanol orethanol, aprotic dipolar solvent, such as dimethylformamide, dimethylsulfoxide or pyridine, in particular acetonitrile, ethanol,dimethylformamide and corresponding mixtures.

Not less than an equivalent amount of a base is usually used, but thebase may also be used in excess or, if necessary, as a solvent. Examplesof suitable bases are hydroxides of alkali metals and of alkaline earthmetals, such as sodium hydroxide, potassium hydroxide and calciumhydroxide, alcoholates of alkali metals and of alkaline earth metals,such as sodium methylate, sodium ethylate, calcium methylate orpotassium tert-butylate, alkali metal or alkaline earth metal hydrides,such as sodium hydride, potassium hydride or calcium hydride, alkalimetal or alkaline earth metal carbonates, such as sodium carbonate,potassium carbonate or calcium carbonate, aliphatic amines, such asdimethylamine, triethylamine or diisopropylamine, heterocyclic amines,such as piperidine, piperazine or pyrrolidine, aromatic amines, such aspyridine or pyrrole and, if required, also alkyllithium compounds, suchas n-butyllithium, in particular potassium hydroxide, potassiumcarbonate, sodium methylate, sodium ethylate, potassium tertbutylate andsodium hydride.

The starting materials are usually reacted with one another instoichiometric amounts, but, in order to increase the yield, it may beadvantageous to use one of the starting materials in an excess of from0.1 to 10, in particular from 0.2 to 1.5, mole equivalents. It may alsobe advantageous to add from 5 to 20 mol % of potassium iodide.

The reaction mixtures are usually worked up in a conventional manner,for example by adding water, separating the phases and purifying thecrude products by means of column chromatography. Some of the novelcompounds of the formula I are obtained in the form of colorless orslightly brownish, viscous oils, which can be freed from the finalvolatile constituents by prolonged heating at moderately elevatedtemperatures under reduced pressure (incipient distillation) and can bepurified in this manner. If the compounds of the formula IVa, IVb or Iare obtained in crystalline form, they can be purified byrecrystallization.

Splitting off of the protective group R from the diethers IVa or IVb canlikewise be effected in a conventional manner in an inert organicsolvent in the presence of an acid at from -20° to 120° C., preferablyfrom 20° to 100° C.

Solvents such as the abovementioned ones, in particular methanol,ethanol, chloroform and dioxane and corresponding mixtures, aregenerally suitable for this purpose.

Suitable acids are inorganic acids, such as hydrofluoric acid,hydrochloric acid, hydrobromic acid, sulfuric acid or perchloric acid,and organic acids, such as formic acid, acetic acid, propionic acid,oxalic acid, citric acid or trifluoroacetic acid, in particularhydrochloric acid, hydrobromic acid or trifluoroacetic acid.

The acids are added in general in catalytic amounts but may also be usedin equimolar amounts, in excess or, if required, as solvents.

The reaction mixtures are worked up in a conventional manner, forexample as described above for the etherification.

Symmetric hydroquinone diethers I (A--X═B--Y) are particularlyadvantageously obtainable in a single-stage reaction by etherificationof unsubstituted or substituted hydroquinones by the etherificationmethods described above. ##STR4##

The hetarylalkyl derivatives of the formulae IIIa and IIIb are eitherknown or are commercially available or can be prepared by generallyknown chemical methods.

Processes for the preparation of thiophene derivatives are described in,for example, Comprehensive Heterocyclic Chemistry, R. Katritzky and W.Rees, Vol. 4, page 863 et seq., Pergamon Press 1984, and thiazolederivatives, oxazole derivatives, isothiazole derivatives, thiadiazolederivatives and oxadiazole derivatives are described in, for exampleComprehensive Heterocyclic Chemistry, R. Katritzky and W. Rees, Vol. 6,pages 131, 177, 235, 365, 427 and 545 et seq., Pergamon Press 1984,imidazole derivatives are described in, for example, Advances inHeterocyclic Chemistry, 27 (1980), 242 et seq., pyrazole and triazolederivatives are described in, for example, Comprehensive HeterocyclicChemistry, R. Katrizky and W. Rees, Vol. 5, pages 167 and 733 et seq.,Pergamon Press 1984, and isoxazole derivatives are described in, forexample, DE-A-25 49 962 and DE-A-27 54 832, and some N-methylazoles aredisclosed in Heterocycles 24 (1986), 2233-2237 or can be obtained by themethod described there, by reacting the azole with paraformaldehyde.

In view of the biological action of the hydroquinone diethers of theformula I, suitable substituents are the following radicals:

R¹ is hydrogen,

halogen, such as fluorine, chlorine, bromine or iodine, in particularfluorine,

alkyl, such as methyl, ethyl, propyl, 1-methylethyl, butyl,1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl,1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 1,1-dimethylpropyl,1,2-dimethylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl,1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl,1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl,2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl,2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl,1-ethyl-1-methylpropyl or 1-ethyl-2-methylpropyl, preferably C₁ -C₄-alkyl, in particular methyl, ethyl or isopropyl,

A and B independently of one another are each methylene, ethylene orpropylene, where these groups may carry one or two alkyl radicals of 1to 3 carbon atoms as stated above for R¹, in particular methyl or ethyl,and X and Y independently of one another are each a 5-memberedheteroaromatic structure containing, in addition to carbon atoms, from 1to 3 hetero atoms from the group consisting of nitrogen, oxygen andsulfur, such as furanyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl,pyrazolyl, oxazolyl, thiazolyl, imidazolyl, oxa-2,4-diazolyl,oxa-3,4-diazolyl, thia-2,4-diazolyl, thia-3,4-diazolyl or triazolyl,where these rings may be bonded to the radical A or B via a carbon ringmember or, where present, a nitrogen ring member; these heteroaromaticstructures may furthermore carry from one to three of the followinggroups on the carbon ring members and, where present, on the valentnitrogen ring members:

alkyl as stated for R¹, preferably C₁ -C₄ -alkyl, in particular methyl,ethyl or 1-methylethyl,

haloalkyl, such as fluoromethyl, difluoromethyl, trifluoromethyl,chlorodifluoromethyl, dichlorofluoromethyl, trichloromethyl,1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl,2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl,2,2,2-trichloroethyl or pentafluoroethyl, in particular trifluoromethylor trichloromethyl,

alkoxy, such as methoxy, ethoxy, n-propoxy, 2-methylethoxy, n-butoxy,1-methylpropoxy, 2-methylpropoxy, 1,1-dimethylethoxy, pentyloxy,1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 1,1-dimethylpropoxy,1,2-dimethylpropoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexyloxy,1-methylpentyloxy, 2-methylpentyloxy, 3-methylpentyloxy,4-methylpentyloxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy,1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy,3,3-dimethylbutoxy, 1-ethylbutoxy, 1,1,2-trimethylpropoxy,1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy or1-ethyl-2-methylpropoxy, preferably C₁ -C₄ -alkoxy, in particularmethoxy, ethoxy or 1-methylethoxy,

haloalkoxy, such as difluoromethoxy, trifluoromethoxy,chlorodifluoromethoxy, dichlorofluoromethoxy, 1-fluoroethoxy,2-fluoroethoxy, 2,2-difluoroethoxy, 1,1,2,2-tetrafluoroethoxy,2,2,2-trifluoroethoxy, 2-chloro-1,1,2-trifluoroethoxy orpentafluoroethoxy, in particular trifluoromethoxy or pentafluoroethoxy,

alkoxyalkyl, such as methoxymethyl, methoxyethyl, 2-methoxyethyl,1-methoxypropyl, 2-methoxypropyl, 1-methoxy-1-methylethyl,2-methoxy-1-methylethyl, 1-methoxybutyl, 2-methoxybutyl,1-methoxy-1-methylpropyl, 1-methoxy-2-methylpropyl,2-methoxy-1-methylpropyl, 2-methoxy-2-methylpropyl, ethoxymethyl,1-ethoxyethyl, 2-ethoxyethyl, 1-ethoxypropyl, 2-ethoxypropyl,1-ethoxy-1-methylethyl, 2-ethoxy-1-methylethyl, 1-ethoxybutyl,2-ethoxybutyl, 1-ethoxy-1-methylpropyl, 1-ethoxy-2-methylpropyl,2-ethoxy-1-methylpropyl or 2-ethoxy-2-methylpropyl, in particularmethoxymethyl or ethoxymethyl, cycloalkyl, such as cyclopropyl,cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl or cyclooctyl,preferably cyclopropyl, cyclopentyl or cyclohexyl, in particularcyclopropyl,

alkenyl, in particular ethenyl, 1-propenyl, 2-propenyl, 2-butenyl,1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 2-pentenyl,3-pentenyl or 1,2-dimethyl-2-propenyl, particularly preferably ethenyl,2-propenyl, 2-butenyl or 3-methyl-2-butenyl,

aryl, such as phenyl, 1-naphthyl or 2-naphthyl, preferably phenyl,

arylalkyl, such as C₁ -C₁₀ -alkyl which is substituted by phenyl,1-naphthyl or 2-naphthyl, preferably C₁ -C₆ -alkyl as stated for R¹, inparticular phenyl-substituted C₁ -C₄ -alkyl, such as benzyl,1-phenylethyl, 2-phenylethyl, 1-phenylpropyl, 2-phenylpropyl,1-methyl-1-phenylethyl, 1-methyl-2-phenylethyl or1,1-dimethyl-2-phenylethyl, where the aromatic radicals in turn maycarry from one to five halogen atoms as stated for R¹, in particularfluorine and/or chlorine and/or from one to three of the followinggroups:

C₁ -C₄ -alkyl as stated for R¹, in particular methyl, ethyl,1-methylethyl or 1,1-dimethylethyl,

C₁ -C₄ -haloalkyl as stated above in general and in particular,

C₁ -C₄ -alkoxy as stated above, in paticular methoxy, ethoxy or1-methylethoxy,

C₁ -C₄ -haloalkoxy as stated above in general and in particular,

C₂ -C₄ -alkenyl as stated above in general and in particular and/or

alkylthio, such as methylthio, ethylthio, propylthio, 1-methylethylthio,butylthio, 1-methylpropylthio, 2-methylproylthio or1,1-dimethylethylthio, in articular methylthio; in addition to theabovementioned groups, the 5-membered hetaryl radicals (X, Y) mayfurthermore carry from one to three halogen atoms, such as fluorine,chlorine, bromine or iodine, in particular fluorine, chlorine orbromine, on the carbon ring members.

5-Membered heteroaromatic structures which are particularly preferredsubstituents X or Y are listed below, for the sake of clarity thepossible substituents not being drawn in; the bond to A or B is denotedby ##STR5##

Examples of the particularly preferred compounds of the general formulaeI.A, I.B, I.C, I.D, I.E, I.F and I.G are shown in Tables A to G below.##STR6##

                  TABLE A                                                         ______________________________________                                        (for structure I.A)                                                                                              Substituent                                A        R.sup.1 B           Y     on Y                                       ______________________________________                                        CH.sub.2 H       CH.sub.2    X/Y-1                                            CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1                                            CH(CH.sub.2 CH.sub.3)                                                                  H       CH.sub.2    X/Y-1                                            CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1                                            CH.sub.2 H       CH(CH.sub.2 CH.sub.3)                                                                     X/Y-1                                            CH.sub.2 3-CH.sub.3                                                                            CH.sub.2    X/Y-1                                            CH.sub.2 3-F     CH.sub.2    X/Y-1                                            CH.sub.2 H       CH.sub.2    X/Y-1 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-1 4-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 5-Br                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3                                                                            H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-2 --                                         CH.sub.2 H       CH.sub.2    X/Y-2 4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-2 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-2 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH.sub.2    X/Y-2 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-2 5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-2 4,5-Br,Br                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-15                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-12                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3 ).sub.2                      CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    3-F     CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-13                                                                              2-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 --                                         CH.sub.2 H       CH.sub.2    X/Y-6 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-6 3-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-6 3-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-8 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3 ,                                                                  5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-10                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-7 --                                         CH.sub.2 H       CH.sub.2    X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      3-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                             X/Y-7 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-9 1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub. 3)                                                                             X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-25                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-23                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-22                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-OCH.sub.3                                CH(CH.sub. 3)                                                                          H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-22                                                                              3-OCH.sub.3                                CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 3-F     CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-14                                                                              5-Cl                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-20                                                                              1-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 --                                         CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-3 3-OCHICH.sub.3                             CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 OCH.sub.3                       CH.sub.2 H       C"2         X/Y-3 3-CF3                                      CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-5 --                                         CH.sub.2 H       CH.sub.2    X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-5 5-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-5 5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-4 --                                         CH.sub.2 H       CH.sub.2    X/Y-4 3-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-4 5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-11                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-11                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-11                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-11                                                                              3-CH.sub.3                                 CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-11                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-11                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-21                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4-5-Cl.sub.2                               CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-Br.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-Cl.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-(CH.sub.3).sub. 2                      CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-Br.sub.2                               CH.sub.2 H       CH.sub.2    X/Y-30                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-30                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       ______________________________________                                    

                  TABLE B                                                         ______________________________________                                        (for structure I.B)                                                                                              Substituent                                A        R.sup.1 B           Y     on Y                                       ______________________________________                                        CH.sub.2 H       CH.sub.2    X/Y-1                                            CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1                                            CH(CH.sub.2 CH.sub.3)                                                                  H       CH.sub.2    X/Y-1                                            CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1                                            CH.sub.2 H       CH(CH.sub.2 CH.sub.3)                                                                     X/Y-1                                            CH.sub.2 3-CH.sub.3                                                                            CH.sub.2    X/Y-1                                            CH.sub.2 3-F     CH.sub.2    X/Y-1                                            CH.sub.2 H       CH.sub.2    X/Y-1 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-1 4-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 5-Br                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3                                                                            H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-2 --                                         CH.sub.2 H       CH.sub.2    X/Y-2 4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-2 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-2 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH.sub.2    X/Y-2 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-2 5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-2 4,5-Br,Br                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-15                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-12                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3 ).sub.2                      CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    3-F     CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-13                                                                              2-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 --                                         CH.sub.2 H       CH.sub.2    X/Y-6 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-6 3-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-6 3-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-8 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3 ,                                                                  5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-10                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-7 --                                         CH.sub.2 H       CH.sub.2    X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      3-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                             X/Y-7 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-9 1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub. 3)                                                                             X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-25                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-23                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-22                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-22                                                                              3-OCH.sub.3                                CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub. 2   X/Y-17                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H-      CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 3-F     CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-14                                                                              5-Cl                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-20                                                                              1-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 --                                         CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-3 3-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 OCH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-3 3-CF.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH(CH.sub.3 )                                                                          H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-5 --                                         CH.sub.2 H       CH.sub.2    X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-5 5-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3 )                                                                             X/Y-5 5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-4 --                                         CH.sub.2 H       CH.sub.2    X/Y-4 3-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-4 5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-11                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-1l                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1l                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1l                                                                              3-CH.sub.3                                 CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-1l                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-1l                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-21                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-Br.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-Cl.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub. 3)                                                                             X/Y-21                                                                              4,5-Br.sub.2                               CH.sub.2 H       CH.sub.2    X/Y-30                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-30                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       ______________________________________                                    

                  TABLE C                                                         ______________________________________                                        (for structure I.C)                                                                                              Substituent                                A        R.sup.1 B           Y     on Y                                       ______________________________________                                        CH.sub.2 H       CH.sub.2    X/Y-1                                            CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1                                            CH(CH.sub.2 CH.sub.3)                                                                  H       CH.sub.2    X/Y-1                                            CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1                                            CH.sub.2 H       CH(CH.sub.2 CH.sub.3)                                                                     X/Y-1                                            CH.sub.2 3-CH.sub.3                                                                            CH.sub.2    X/Y-1                                            CH.sub.2 3-F     CH.sub.2    X/Y-1                                            CH.sub.2 H       CH.sub.2    X/Y-1 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-1 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-1 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-1 4-Br                                       CH.sub.2 H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-1 4-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 5-Br                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-1 4-Cl                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3                                                                            H       CH(CH.sub.3)                                                                              X/Y-1 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 --                                         CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-1 5-Br                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-1 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-1 5-Br                                       CH.sub.2 H       CH.sub.2    X/Y-2 --                                         CH.sub.2 H       CH.sub.2    X/Y-2 4-Cyclopropy                               CH.sub.2 H       CH.sub.2    X/Y-2 5-Cyclopropy                               CH.sub.2 H       CH.sub.2    X/Y-2 5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH.sub.2    X/Y-2 4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-2 4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-2 5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-2 4,5-Br,Br                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Cl,Cl                                  CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-2 4,5-Cl,Cl                                  CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-2 4,5-Br,Br                                  CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-2 4,5-Br,Br                                  CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-2 4,5-Cl,Cl                                  CH.sub.2 H       CH.sub.2    X/Y-15                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-15                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-15                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-15                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-12                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH(CH.sub.3)                                                                              X/Y-12                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-12                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-12                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-18                                                                              1,2,4-(CH.sub.3).sub.3                     CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-18                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-18                                                                              1,2,4-(CH.sub.3).sub.2                     CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3 ).sub.2                      CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-19                                                                              1-CH.sub.3,                                                                   2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-19                                                                              1,2-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-16                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3 )                                                                          H       CH.sub.2    X/Y-16                                                                              2-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    3-F     CH(CH.sub.3)                                                                              X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-16                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-16                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-13                                                                              2-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-13                                                                              2-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-13                                                                              2-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-13                                                                              2-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 --                                         CH.sub.2 H       CH.sub.2    X/Y-6 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-6 3-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-6 3-CH.sub.3                                 CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-6 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH(CH.sub.3)CH.sub.2                                                                      X/Y-6 3-Cyclopropyl                              CH.sub.2 H       CH.sub. 2   X/Y-8 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-8 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-8 1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   4-OCH.sub.3                                CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-10                                                                              1,4-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-10                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-10                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-7 --                                         CH.sub.2 H       CH.sub.2    X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-7 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      3-F     CH(CH.sub.3)CH.sub.2 CH.sub.2                                                             X/Y-7 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-9 1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3 )                                                                             X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 CH(CH.sub.3)                                                                  H       CH.sub.2 CH.sub.2                                                                         X/Y-9 1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH.sub.2 CH.sub.2                                                                         X/Y-9 1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 (CH.sub.3)                                                                    H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2    X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-25                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-25                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      3-F     CH.sub.2 CH(CH.sub.3)                                                                     X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-25                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-23                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-23                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2 CH.sub.2                                                             H       CH.sub.2    X/Y-23                                                                              5-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-23                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-26                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH.sub.2    X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1-CH.sub.3,                                                                   5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-28                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-22                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-22                                                                              3-OCH.sub.3                                CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-22                                                                              3-OCH.sub.3                                CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-22                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-29                                                                              1,3-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-29                                                                              1-CH.sub.3,                                                                   3-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              5-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-17                                                                              4-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-17                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-17                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-17                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-17                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-14                                                                              4-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-14                                                                              5-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-14                                                                              4-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 3-F     CH.sub.2    X/Y-14                                                                              5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              5-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-14                                                                              5-Cl                                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-14                                                                              4-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-20                                                                              1-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2                                                                         X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH(CH.sub.3)CH.sub.2                                                                   3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-20                                                                              1,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 --                                         CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 CH.sub.3                        CH.sub.2 H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-3 3-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-3 3-CH.sub.2 OCH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-3 3-CF3                                      CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-3 3-CH(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-3 3-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-CH.sub.3                                 CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-Cyclopropyl                              CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH(CH.sub.3)                                                                     X/Y-3 3-CH(CH.sub.3).sub.2                       CH.sub.2 CH.sub.2 CH.sub.2                                                             3-F     CH(CH.sub.3)CH.sub.2                                                                      X/Y-3 3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-5 --                                         CH.sub.2 H       CH.sub.2    X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2    X/Y-5 5-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-5 5-Cyclopropyl                              CH(CH.sub.3)                                                                           H       CH.sub.2    X/Y-5 5-Cyclopropyl                              CH.sub.2 H       CH.sub.2 CH.sub.2                                                                         X/Y-5 5-OCH.sub.2 CH.sub.3                       CH.sub.2 CH.sub.2                                                                      H       CH.sub.2 CH.sub.2 CH.sub.2                                                                X/Y-5 5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-4 --                                         CH.sub.2 H       CH.sub.2    X/Y-4 3-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 5-OCH.sub.2 CH.sub.3                       CH.sub.2 H       CH.sub.2    X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-4 5-CH.sub.3                                 CH(CH.sub.3)                                                                           3-F     CH(CH.sub.3)                                                                              X/Y-4 3-CH(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-11                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-11                                                                              3-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-11                                                                              5-CH.sub.3                                 CH.sub.2 H       CH(CH.sub.3)                                                                              X/Y-11                                                                              3-CH.sub.3                                 CH.sub.2 3-F     CH(CH.sub.3)                                                                              X/Y-11                                                                              5-CH.sub.3                                 CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-11                                                                              5-CH.sub.3                                 CH.sub.2 H       CH.sub.2    X/Y-21                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-21                                                                              4,5-Br.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-Cl.sub.2                               CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-21                                                                              4,5-Br.sub.2                               CH.sub.2 H       CH.sub.2    X/Y-30                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-30                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3 )                                                                             X/Y-30                                                                              3,5-(CH.sub.3).sub.2                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              --                                         CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2-Cl                                       CH.sub.2 H       CH.sub.2    X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              --                                         CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2-Cl                                       CH(CH.sub.3)                                                                           H       CH(CH.sub.3)                                                                              X/Y-27                                                                              2,5-(CH.sub.3).sub.2                       ______________________________________                                    

                                      TABLE D                                     __________________________________________________________________________    (for structure I.D)                                                           A       R.sup.1                                                                           B        Y    Substituent on Y                                    __________________________________________________________________________    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                    CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                    CH(CH.sub.2 CH.sub.3)                                                                 H   CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.2 CH.sub.3)                                                                  X/Y-1                                                    CH.sub.2                                                                              3-CH.sub.3                                                                        CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              3-F CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3                                                                           H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-OCH.sub.3                                         CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub. 3)                                                                         3-F CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub. 3                             CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-19                                                                             1-CH.sub.3 , 2-Cyclopropyl                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   3-F CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-Cyclopropryl                                      CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-13                                                                             2-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-6                                                                              3-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3 , 3-Cyclopropyl                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 4-OCH.sub.3                             CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-CH(CH.sub.3).sub.2                    CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-10                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3 )                                                                         H   CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     3-F CH(CH.sub.3)CH.sub.2 CH.sub.2                                                          X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub. 2                                                                             H   CH.sub.2 X/Y-22                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-22                                                                             3-OCH.sub.3                                         CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cl                                                CH.sub. 2                                                                             H   CH.sub.2 X/Y-17                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH.sub. 2                                                                             3-F CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-14                                                                             5-Cl                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-20                                                                             1-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 OCH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CF.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3 )                                                                          X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-5                                                                              5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-Br.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Cl.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Br.sub.2                                        CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                __________________________________________________________________________

                                      TABLE E                                     __________________________________________________________________________    (for structure I.E)                                                           A       R.sup.1                                                                           B        Y    Substituent on Y                                    __________________________________________________________________________    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                    CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                    CH(CH.sub.2 CH.sub.3)                                                                 H   CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.2 CH.sub.3)                                                                  X/Y-1                                                    CH.sub.2                                                                              3-CH.sub.3                                                                        CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              3-F CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3                                                                           H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-OCH.sub.3                                         CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br, Br                                          CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3 )                                                                          X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   3-F CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub. 2                                                                    H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-13                                                                             2-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-6                                                                              3-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub. 2 CH.sub.2                                                                     X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 4-OCH.sub.3                             CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-CH(CH.sub.3).sub.2                    CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-10                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              --                                                  CH.sub.2                                                                              H   CH.sub. 2                                                                              X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     3-F CH(CH.sub.3)CH.sub.2 CH.sub.2                                                          X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-CH(CH.sub.3).sub. 2                               CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.2)                                                                           X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-22                                                                             3-OCH.sub.3                                         CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              3-F CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-14                                                                             5-Cl                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-20                                                                             1-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 OCH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CF.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub. 2                               CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-5                                                                              5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub. 2                                                                              X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-Br.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Cl.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Br.sub.2                                        CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.2)                                                                           X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                __________________________________________________________________________

                                      TABLE F                                     __________________________________________________________________________    (for structure I.F)                                                           A       R.sup.1                                                                           B        Y    Substituent on Y                                    __________________________________________________________________________    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                    CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                    CH(CH.sub.2 CH.sub.3)                                                                 H   CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.2 CH.sub.3)                                                                  X/Y-1                                                    CH.sub.2                                                                              3-CH.sub.3                                                                        CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              3-F CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3                                                                           H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-OCH.sub.3                                         CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub. 2 CH.sub.3                               CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   3-F CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-13                                                                             2-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-6                                                                              3-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 4-OCH.sub.3                             CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-CH(CH.sub.3).sub.2                    CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-10                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     3-F CH(CH.sub.3)CH.sub.2 CH.sub.2                                                          X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2CH.sub.2                                                                       X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-22                                                                             3-OCH.sub.3                                         CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-OCH.sub. 2 CH.sub.3                               CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-CH.sub. 3                                         CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              3-F CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-14                                                                             5-Cl                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-20                                                                             1-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub. 2 OCH.sub.3                               CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CF.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub. 2                                                                             H   CH.sub.2 X/Y-5                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-5                                                                              5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-Br.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub. 3)                                                                          X/Y-21                                                                             4,5-Cl.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Br.sub.2                                        CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                __________________________________________________________________________

                                      TABLE G                                     __________________________________________________________________________    (for structure I.G)                                                           A       R.sup.1                                                                           B        Y    Substituent on Y                                    __________________________________________________________________________    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                    CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                    CH(CH.sub.2 CH.sub.3)                                                                 H   CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                    CH.sub.2                                                                              H   CH(CH.sub.2 CH.sub.3)                                                                  X/Y-1                                                    CH.sub.2                                                                              3-CH.sub.3                                                                        CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              3-F CH.sub.2 X/Y-1                                                    CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-1                                                                              4-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-1                                                                              4-Cl                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3                                                                           H   CH(CH.sub.3)                                                                           X/Y-1                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              --                                                  CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-1                                                                              5-Br                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-1                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-1                                                                              5-Br                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              4-OCH.sub.3                                         CH.sub.2                                                                              H   CH.sub.2 X/Y-2                                                                              5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Cl,Cl                                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-2                                                                              4,5-Br,Br                                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-2                                                                              4,5-Cl,Cl                                           CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-15                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub. 2 CH.sub.3                               CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-15                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-15                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-12                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-12                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-12                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-18                                                                             1,2,4-(CH.sub.3).sub.3                              CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-18                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-18                                                                             1,2,4-(CH.sub.3).sub.2                              CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-19                                                                             1-CH.sub.3, 2-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-19                                                                             1,2-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-16                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   3-F CH(CH.sub.3)                                                                           X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-16                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-16                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-13                                                                             2-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-13                                                                             2-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-13                                                                             2-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-13                                                                             2-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-6                                                                              3-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-6                                                                              3-CH.sub.3                                          CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH(CH.sub.3)CH.sub.2                                                                   X/Y-6                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-8                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-8                                                                              1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 4-OCH.sub.3                             CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-CH(CH.sub.3).sub.2                    CH.sub.2                                                                              H   CH.sub.2 X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-10                                                                             1,4-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-10                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-10                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     3-F CH(CH.sub.3)CH.sub.2 CH.sub.2                                                          X/Y-7                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2 CH(CH.sub.3)                                                                 H   CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH.sub.2 CH.sub.2                                                                      X/Y-9                                                                              1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 (CH.sub.3)                                                                   H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-25                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-25                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     3-F CH.sub.2 CH(CH.sub.3)                                                                  X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-25                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-23                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2 CH.sub.2                                                            H   CH.sub.2 X/Y-23                                                                             5-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub. 2 CH.sub.2                                                                     X/Y-23                                                                             5-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-23                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-26                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-26                                                                             1,5(CH.sub.3).sub.2                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH.sub.2 X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1-CH.sub.3, 5-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-28                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-22                                                                             3-OCH.sub.3                                         CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-22                                                                             3-OCH.sub.3                                         CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-22                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-29                                                                             1,3-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-29                                                                             1-CH.sub.3, 3-Cyclopropyl                           CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             5-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-17                                                                             4-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-17                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-17                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-17                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-17                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             4-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-14                                                                             5-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-14                                                                             4-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2                                                                              3-F CH.sub.2 X/Y-14                                                                             5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             5-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-14                                                                             5-Cl                                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-14                                                                             4-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-20                                                                             1-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2                                                                      X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH(CH.sub.3)CH.sub.2                                                                  3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-20                                                                             1,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 CH.sub.3                                 CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CH.sub.2 OCH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-3                                                                              3-CF.sub.3                                          CH(CH.sub.3 )                                                                         H   CH.sub.2 X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-Cyclopropyl                                       CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH(CH.sub.3)                                                                  X/Y-3                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2 CH.sub.2 CH.sub.2                                                            3-F CH(CH.sub.3)CH.sub.2                                                                   X/Y-3                                                                              3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 X/Y-5                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3 )                                                                          X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-5                                                                              5-Cyclopropyl                                       CH(CH.sub.3)                                                                          H   CH.sub.2 X/Y-5                                                                              5-Cyclopropyl                                       CH.sub.2                                                                              H   CH.sub.2 CH.sub.2                                                                      X/Y-5                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2 CH.sub.2                                                                     H   CH.sub.2 CH.sub.2 CH.sub.2                                                             X/Y-5                                                                              5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-OCH.sub.2 CH.sub.3                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-4                                                                              5-CH.sub.3                                          CH(CH.sub.3)                                                                          3-F CH(CH.sub.3)                                                                           X/Y-4                                                                              3-CH(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH(CH.sub.3)                                                                           X/Y-11                                                                             3-CH.sub.3                                          CH.sub.2                                                                              3-F CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-11                                                                             5-CH.sub.3                                          CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-21                                                                             4,5-Br.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Cl.sub.2                                        CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-21                                                                             4,5-Br.sub.2                                        CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-30                                                                             3,5-(CH.sub.3).sub.2                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             --                                                  CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2-Cl                                                CH.sub.2                                                                              H   CH.sub.2 X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             --                                                  CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2-Cl                                                CH(CH.sub.3)                                                                          H   CH(CH.sub.3)                                                                           X/Y-27                                                                             2,5-(CH.sub.3).sub.2                                __________________________________________________________________________

The hydroquinone diethers of the formula I are suitable for effectivelycontrolling pests from the class consisting of the insects, arachnidsand nematodes. They can be used as pesticides in crop protection and inthe hygiene and veterinary sectors and for the protection of storedmaterial.

The insect pests include, from the order of the butterflies(Lepidoptera), for example, Agrotis ypsilon, Agrotis segetum, Alabamagrillacea, Anticarsia gemmatalis, Argyesthia conjugella, Autographagamma, Bupulus piniarius, Cacoecia murinana, Capua reticulana,Cheimatobia brumata, Choristoneura fumiferana, Choristoneuraoccidentalis, Cirphis unipuncta, Cydia pomonell, Dendrolimus pini,Diaphania nitidalis, Diatraea grandiosella, Earias insulana,Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana,Feltia subterranea, Galleria mellonella, Grapholita funebrana,Grapholita molesta, Heliothis armigera, Heliothis virescens, Heliothiszea, Hellula undalis, Hibernia defoliara, Hyphantria cunea, Hyponomeutamalinellus, Keifferia lycopersicella, Lambdina fiscellaria, Laphygmaexigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletisblancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar,Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestrabrassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flamea,Pectinophora gossypiella, Peridroma saucia, Phalera bucephala,Phthorimaea operculella, Phyllocnistris citrella, Pieris brassicae,Plathypena scarbra, Plutella xylostella, Pseudoplusia includens,Phyacionia frustrana, Scrobipalpula absoluta, Sitotroga Cerelella,Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis,Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana,Trichloplusia ni and Zeiraphera canadensis; from the order of thebeetles (Coleoptera), for example, Agrilius sinuatus, Agriotes lineatus,Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar,Anthonomus grandis, Anthonomus pomorum, Atomaria linearis, Blastophaguspiniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum,Bruchus lentis, Byctiscus betular, Cassida Nebulos, Cerotoma trifurcata,Ceuthorrhynchus assimils, Ceuthorrynchus napi, Chaetocnema tibialis,Conoderus vespertinus, Crioceris asparagi, Diabrotics longicornis,Diabrotica 12-punctat, Diagrotica virgifera, Epilachna varivestis,Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis,Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata,Lema melanopus, Leptinotarsa decemlineata, Limonius californicus,Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus,Melolontha hippocastani, Melolontha melolontha, Onlema oryzae,Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae,Phyllotreta crysocephala, Phyllophaga sp., Phyllopertha horitcola,Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitaonlineatus or Sitophilus granaria;

from the order of the Diptera, for example, Aedes aegypti, Aedes vexans,Anastrepha ludens, Anopheles maculipennis, Ceratitis capitat, Chrysomyaezziana, Chrysomya hominivorax, Chrysomya macellaria, Contrainiasorphicola, Cordylobia anthropophaga, Culex pipiens, Dacus cucurbitae,Dacus oleae, Dasineura brassicae, Fannia canicularis, Gasterophilusintestinalis, Glossia morsitans, Haematobia irritans, Haplodilosisequestris, Hylemyia platura, Hyoderma lineata, Liriomyza sativae,Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata,Lycoria pectoralis, Mayetiola destructor, Musca domestica, Muscinastabulans, Oestrus ovis, Oscinella frit, Pegomya hysocyami, Phorbiaantiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletic cerasi,Rhagoletis pomonella, Tabaus bovinus, Tipula oleracea and Tipulapaludosa;

from the order of the thrips (Thysanoptera), for example, Frankliniellafusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothripscitri, Thrips oryzae, Thrips palmi, Thrips tabaci;

from the order of the Hymenopters, for example, Athalia rosae, Attacephalotes, Atta sexdens, Atta texana, Hoplocampa minuta, Hoplocampatestudinea, Monomorium pharaonis, Solenopsis geminata and Solenopsisinvicta;

from the order of the Heteroptera, for example, Acrosternum hilare,Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus,Dysdercus intermedius, Eurygaster integriceps, Euchistus impictiventris,Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezaraviridula, Piesma quadrata, Solubea insularis and Thyanta perditor;

from the order of the Homoptera, for example, Acyrthosiphon onobrychis,Adelges laricis, Ahidula nasturtii, Aphis fabae, Aphis pomi, Aphissambuci, Brachycaudus cardui, Brevicornyne brassicae, Cerosiphagossypii, Dreyfusia nordmannianae, Dreyfusia piceae, Dyasphis radicola,Dysaulacorthum pseudosolani, Empoasca fabae, Macrosiphum avenae,Macrosiphum euphorbiae, Macrosiphon rasae, Megoura viciae, Metopolophiumdirhodum, Myzodes persicae, Myzus cerasi, Nilaparvata lugens, Pemphigusbursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali,Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Sappaphismala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa,Trialeurodes vaporariorum and Viteus vitifolii;

from the order of the termites (Isoptera), for example, Calotermesfalvicollis, Leucotermes flavipes, Reticulitermes lucifugus and Termesnatalensis; from the order of the Orthoptera, for example, Achetadomestica, Blatta orientalis, Blattella germanica, Forficulaauricularia, Gryllotalpa gryllotalpa, Locusta micrgatoria, Melanoplusbirittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplussanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplanetaamericana, Schistocerca americana, Schistocerca peregrina, Stauronotusmaroccanus and Tachycines asynamorus;

from the class of the Arachnoidea, for example, acarina, such asAmblyomma americanum, Amglyomma variegatum, Argas persicus, Boophililusannulatus, Boohilus decolaratus, Boophilus microplus, Brevipalpusphoenicis, Bryobia praetiosa, Dermacentor silvarum, Eotetranychuscarpini, Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodesrubicundus, Ornithodorus moubata, Otobins megnini, Paratetranychuspilosus, Permanyssus gallinae, Phyllocaptrata oleivora,Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus,Rhipicephalus evertsi, Saccoptes scabiei, Tetranychus cinnabarinus,Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius andTetranychus urticae; from the class of the nematodes, for example, rootgall nematodes, for example Meloidogyne hapla, Meloidogyne incognita,Meloidogny javanica, cyst-forming Nematoden, e.g., Globoderarostochiensis, Heterodera avenae, Heterodera glycinae, Heteroderaschatii, Hetrodera triflolii, stem and leaf eelworms, e.g., Belonolaimuslongicaudatus, Ditylenchus destructor, Ditylenchus dipsaci,Heliocotylenchus multicinctus, Longidorus elongatus, Radopholus similis,Rotylenchus robustus, Trichodorus primitivus, Tylenchorhynchus claytoni,Tylenchorhynchus dubius, Pratylenchus neglectus, Pratylenchus penetrans,Pratylenchus curvitatus and Pratylenchus goodeyi.

The active ingredients can be used as such, in the form of theirformulations or in the application forms prepared therefrom, for examplein the form of directly sprayable solutions, powders, suspensions ordispersions, emulsions, oil dispersions, pastes, dusting agents,broadcasting agents or granules, by spraying, atomizing, dusting,broadcasting or pouring. The application forms depend entirely on theintended uses; they should in any case ensure very fine distribution ofthe novel active ingredients.

For the preparation of directly sprayable solutions, emulsions, pastesor oil dispersions, mineral oil fractions having a medium to highboiling point, such as kerosene or diesel oil, and coal tar oils andoils of vegetable or animal origin, aliphatic, cyclic and aromatichydrocarbons, e.g., benzene, toluene, xylene, paraffin,tetrahydronaphthalene, alkylated naphthalenes or their derivatives,methanol, ethanol, propanol, butanol, chloroform, carbon tetrachloride,cyclohexanol, cyclohexanone, chlorobenzene, isophorone, as stronglypolar solvents, e.g., dimethylformamide, dimethyl sulfoxide,N-methylpyrrolidone or water, are suitable.

Aqueous application forms can be prepared from emulsion concentrations,pastes or wettable powders (spray powders, oil dispersion) by addingwater. For the preparation of emulsions, pastes or oil dispersions, thesubstances as such can be dissolved in an oil or solvent and can behomogenized in water by means of wetting agents, adhesives, dispersantsor emulsifiers. However, concentrates which consist of active substance,wetting agents, adhesives, dispersants or emulsifiers and, if required,solvents or oil and which are suitable for dilution with water can alsobe prepared.

Suitable surfactants are alkali metal, alkaline earth metal and ammoniumsalts of ligninsulfonic acid, naphthalenesulfonic acid, phenolsulfonicacid and dibutylnaphthalenesulfonic acid, alkylarylsulfonates,alkylsulfates, alkylsulfaonates, fatty alcohol sulfates and fatty acidsand their alkali metal and alkaline earth metal salts, salts of sulfatedfatty alcohol glycol ethers, condensates of sulfonated naphthalene andnaphthalene derivatives with formaldehyde, condensates of naphthalene orof naphthalenesulfonic acid with phenol and formaldehyde,polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol,octylphenol, nonylphenol, alkylphenol polyglycol ethers, tributylphenylpolyglycol ethers, alkylaryl polyether alcohols, isotridecyl alcohol,fatty alcohol/ethylene oxide condensates, ethoxylated castor oil,polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, laurylalcohol polyglycol ether acetal, sorbitol esters, ligninsulfite wasteliquors and methylcellulose.

Powders, broadcasting agents and dusting agents can be prepared bymixing or milling the active substances together with a solid carrier.

The formulations contain in general for 0.01 to 95, preferably from 0.1to 90, % by weight of the active ingredient. The active ingredients areused in a purity of from 90 to 100%, preferably from 95 to 100%(according to NMR spectrum).

Examples of formulations are:

I. 5 parts by weight of compound No. 1.010 are thoroughly mixed with 95parts by weight of finely divided kaolin. A dusting agent which contains5% by weight of the active ingredient is obtained in this manner.

30 parts by weight of compound No. 1.001 are thoroughly mixed with amixture of 92 parts by weight of silica gel powder and 8 parts by weightof liquid paraffin which has been sprayed onto the surface of thissilica gel. A formulation of the active ingredient having good adhesion(active ingredient content 23% by weight) is obtained in this manner.

III. 10 parts by weight of compound No. 1.013 are dissolved in a mixturewhich consists of 90 parts by weight of xylene, 6 parts by weight of theadduct of from 8 to 10 moles of ethylene oxide with 1 mole of oleic acidN-monoethanolamide, 2 parts by weight of the calcium salt ofdodecylbenzenesulfonic acid and 2 parts by weight of the adduct of 40moles of ethylene oxide with 1 mole of castor oil (active ingredientcontent 9% by weight).

IV. 20 parts by weight of compound No. 1.007 are dissolved in a mixturewhich consists of 60 parts by weight of cyclohexanone, 30 parts byweight of isobutanol, 5 parts by weight of the adduct of 7 moles ofethylene oxide with 1 mole of isooctylphenol and 5 parts by weight ofthe adduct of 40 moles of ethylene oxide with 1 mole of castor oil(active ingredient content 16% by weight).

V. 80 parts by weight of compound No. 1.008 are thoroughly mixed with 3parts by weight of the sodium salt ofdiisobutylnaphthalene-alpha-sulfonic acid, 10 parts by weight of thesodium salt of a ligninsulfonic acid obtained from a sulfite wasteliquor and 7 parts by weight of silica gel powder, and the mixture ismilled in a hammer mill (active ingredient content 80% by weight).

VI. 90 parts by weight of a compound No. 1.003 are mixed with 10 partsby weight of N-methyl-60-pyrrolidone, and a solution which is suitablefor the use in the form of very small drops is obtained (activeingredient content 90% by weight).

VII. 20 parts by weight of compound No. 1.005 are dissolved in a mixturewhich consists of 40 parts by weight of cyclohexanone, 30 parts byweight of isobutanol, 20 parts by weight of the adduct of 7 moles ofethylene oxide with 1 mole of isooctylphenol and 10 parts by weight ofthe adduct of 40 moles of ethylene oxide with 1 mole of castor oil. Bypouring the solution into 100,000 parts by weight of water and finelydistributing it therein, an aqueous dispersion which contains 0.02% byweight of the active ingredient is obtained.

VIII. 20 parts by weight of active ingredient No. 1.011 are thoroughlymixed with 3 parts by weight of the sodium salt ofdiisobutylnaphthalene-60-sulfonic acid, 17 parts by weight of the sodiumsalt of a ligninsulfonic acid obtained from a sulfite waste liquor and60 parts by weight of silica gel powder, and the mixture is milled in ahammer mill. By finely distributing the mixture in 20,000 parts byweight of water, a spray liquor which contains 0.1% by weight of theactive ingredient is obtained.

Granules, for example coated, impregnated and homogeneous granules, canbe prepared by binding the active ingredients to solid carriers.Examples of solid carriers are mineral earths, such as silica gel,silicas, silicates, talc, kaolin, attaclay, limestone, lime, chalk,bole, loess, clay, dolomite, kieselguhr, calcium sulfate, magnesiumsulfate, magnesium oxide, milled plastics, fertilizers, e.g., ammoniumsulfate, ammonium phosphate, ammonium nitrate and ureas, and vegetableproducts, such as cereal meal, ground bark, woodmeal, nutshell meal andcellulose powder, and other solid carriers.

The active ingredient concentrations in the ready-to-use formulationscan be varied within wide ranges.

In general, they are from 0.0001 to 10%, preferably from 0.01 to 1%.

The active ingredients can also be successfully used by the ultra lowvolume method (ULV), it being possible to apply formulations containingmore than 95% of active ingredient or even the active ingredient withoutadditives.

The application rate of active ingredient under open air conditions isfrom 0.001 to 10, preferably from 0.1 to 1, kg/ha.

Oils of various types, herbicides, fungicides, other crop protectionagents and bactericides can be added to the active ingredients, ifnecessary directly before application (tank mix). These agents can beadded to the novel agents in a weight ratio of from 1:10 to 10:1.

EXAMPLES OF SYNTHESIS

The working methods described in the examples of synthesis below wereused for preparing further compounds I with appropriate modification ofthe starting materials. The compounds thus obtained are listed in theTables below together with physical data.

Preparation of1-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-methoxy]-4-(4,5-dichloroimidazol-1-ylmethoxy)-benzene##STR7## a)4-tert-Butoxy-1-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-methoxy]-benzene##STR8##

28.5 g (0.172 mol) of 4-tert-butoxyphenol in 260 cm³ ofdimethylformamide (DMF) are added dropwise to 5.7 g of 80% strengthsodium hydride (0.19 mol) in 37 cm³ of DMF. The mixture is stirred fortwo hours at from 40 to 50° C. and then cooled to 25° C., and 30 g of2-chloromethyl-5-cyclopropyl-1,3,4-thiadiazole in 250 cm³ of DMF areadded. Stirring is carried out for 5 hours at 80° C., after which thesolvent is removed, the residue is taken up in water and the solution isextracted with ethyl acetate. The organic phase is dried and evaporateddown.

After flash chromatography over silica gel using cyclohexane/ethylacetate as the mobile phase, the desired product is obtained as whitecrystals of melting point 53°-55° C., in a yield of 50.5% of theory.

b) 1[(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)-methoxy]-4-hydroxybenzene

A few drops of aqueous hydrochloric acid are added to 26.4 g of theproduct from a) in 215 cm³ of ethanol and the mixture is refluxed for 8hours. Evaporation gives the desired product as a white powder ofmelting point 79°-83° C., in quantitative yield.

c)1-[(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)-methoxy]-4-(4,5-dichloroimidazol-1-ylmethoxy)-ben

4.7 g (0.0191 mol) of the product from b) in 25 cm³ of DMF are addeddropwise to 0.63 g (0.021 mol) of 80% strength sodium hydride in 6 cm³of DMF at 25° C. The mixture is stirred for 30 minutes at 25° C., afterwhich 3.54 g (0.0191 mol) of 4,5-dichloro-1-chloromethylimidazole in 10cm³ of DMF are added. Heating is carried out for 4 hours at 80° C.,after which the solvent is removed, the residue is taken up in water andthe solution is extracted with ethyl acetate. The organic phase is driedand evaporated down to give the crude product. After flashchromatography over silica gel using cyclohexane/ethyl acetate as themobile phase, the desired product is obtained as colorless crystals ofmelting point 108°-109° C., in a yield of 5.0 g (66% of theory).

IR: (fingerprint region; cm⁻¹) 1510, 1257, 1236, 1227, 1202, 1034, 825.

                                      TABLE 1                                     __________________________________________________________________________     ##STR9##                                     I                                                                       Phys. data                                                                    [mp(°C.); NMR                  Example no.                                                                          X          A  R.sup.1                                                                         B  Y             (δ in ppm)]                     __________________________________________________________________________    1.001                                                                                 ##STR10## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR11##    121                                   1.002                                                                                 ##STR12## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR13##    128                                   1.003                                                                                 ##STR14## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR15##    108-109                               1.004                                                                                 ##STR16## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR17##    70-71                                 1.005                                                                                 ##STR18## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR19##    123                                   1.006                                                                                 ##STR20## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR21##    102                                   1.007                                                                                 ##STR22## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR23##     91                                   1.008                                                                                 ##STR24## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR25##    117                                   1.009                                                                                 ##STR26## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR27##    97-98                                 1.010                                                                                 ##STR28## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR29##    86-87                                 1.011                                                                                 ##STR30## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR31##    121                                   1.012                                                                                 ##STR32## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR33##     74                                   1.013                                                                                 ##STR34## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR35##    118-120                               1.014                                                                                 ##STR36## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR37##    120-125                               1.015                                                                                 ##STR38## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR39##    82-83                                 1.016                                                                                 ##STR40## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR41##     98-100                               1.017                                                                                 ##STR42## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR43##    165-170                               1.018                                                                                 ##STR44## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR45##    120-125                               1.019                                                                                 ##STR46## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR47##    104-106                               1.020                                                                                 ##STR48## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR49##    102-105                               1.021                                                                                 ##STR50## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR51##    112-121                               1.022                                                                                 ##STR52## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR53##    54-58                                 1.023                                                                                 ##STR54## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR55##    84-87                                 1.024                                                                                 ##STR56## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR57##    86-90                                 1.025                                                                                 ##STR58## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR59##    93- 95                                1.026                                                                                 ##STR60## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR61##    113-117                               1.027                                                                                 ##STR62## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR63##    77-79                                 1.028                                                                                 ##STR64## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR65##    A 5,17  B 5,70                        1.029                                                                                 ##STR66## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR67##    A 5,17  B 5,67                        1.030                                                                                 ##STR68## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR69##    68-72                                 1.031                                                                                 ##STR70## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR71##    76-77                                 1.032                                                                                 ##STR72## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR73##    82-83                                 1.033                                                                                 ##STR74## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR75##    79-85                                 1.034                                                                                 ##STR76## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR77##    63-66                                 1.035                                                                                 ##STR78## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR79##    57-60                                 1.036                                                                                 ##STR80## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR81##    66-69                                 1.037                                                                                 ##STR82## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR83##    60-65                                 1.038                                                                                 ##STR84## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR85##    59-60                                 1.039                                                                                 ##STR86## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR87##    123-128                               1.040                                                                                 ##STR88## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR89##     97-100                               1.041                                                                                 ##STR90## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR91##    81-85                                 1.042                                                                                 ##STR92## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR93##    78-80                                 1.043                                                                                 ##STR94## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR95##    131-134                               1.044                                                                                 ##STR96## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR97##    54-61                                 1.045                                                                                 ##STR98## CH.sub.2                                                                         H CH.sub.2                                                                          ##STR99##    103-105                               1.046                                                                                 ##STR100##                                                                              CH.sub.2                                                                         H CH.sub.2                                                                          ##STR101##   124-126                               1.047                                                                                 ##STR102##                                                                              CH.sub.2                                                                         H CH.sub.2                                                                          ##STR103##   108-110                               __________________________________________________________________________

USE EXAMPLES

The insecticidal action of the compounds of the general formula I isdemonstrated in the following experiments.

The active ingredients were formulated

a) as a 0.1% strength solution in acetone, or

b) as a 10% strength emulsion in a mixture consisting of 70 wt % ofcyclohexanol, 20 wt % of Nekanil® LN (LUtensol® AP6, a spreader-stickerwith an emulsifying and dispersing action based on ethoxylatedalkylphenols) and 10 wt % of Emulphor® EL (Emulan® EL, an emulsifierbased on ethoxylated fatty alcohols)

and diluted down to the desired concentration with acetone in the caseof a) and with water in the case of b).

Upon conclusion of the experiments the lowest concentration wasdetermined at which the compounds, compared with the untreated controlexperiments, achieved 80 to 100% inhibition or kill (action threshold orminimum concentration).

A) Aphis fabae, contact action

Bush beans (Vicia faba) under heavy attack from Aphis fabae were treatedwith aqueous formulations of the active ingredients. The kill rate wasdetermined after 24 hours.

In this test, the action threshold of the candidate compounds was 200 to400 ppm.

B) Dysdercus intermedius, ovicide test

Eggs of Dysdercus intermedius were attached to standard adhesive strips,which were then wetted with aqueous formulations of the activeingredients. After the larvae in the control experiments had hatched(about 8 days) the kill rate was determined.

In this test, the compounds investigated had action thresholds of 2 to1000 ppm.

C)

Prodenia litura, breeding experiment

5 caterpillars of development stage L3 (10 to 12 mm) which had notsuffered any ascertainable damage in the contact experiment were placedon standard nutrient media which had previously been wetted with aqueousformulations of the active ingredients. The experiments was monitoreduntil the moths in a control experiment (without any active ingredient)emerged. In this experiment, the compounds investigated exhibited actionthresholds of 0.4 to 0.000002 ppm.

We claim:
 1. A hydroquinone diether of the formula I ##STR104## where R¹is hydrogen, halogen or C₁ -C₆ -alkyl,A and B are each methylene,ethylene or propylene, where these groups may carry one or two C₁ -C₃-alkyl radicals, and X and Y are each a 5-membered heteroaromaticstructure selected from the group consisting of 2-thienyl, 3-thienyl,3-isoxazolyl, 4-isoxazolyl, 4-isothiazolyl, 5-isothiazolyl, 1-pyrazolyl,2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-thiazolyl, 4-thiazolyl,5-thiazolyl, 4,5-dichloro-1-imidazolyl, 2-imidazoly, 4-imidazolyl,5-imidazolyl, 1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-2-yl,1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl, 1,3,4-triazol-1-yl,1,3,4-triazol-2-yl, 1,2,4-triazol-1-yl, 1,2,4-triazol-3-yl and1,2,4-triazol-5-yl, which may carry from one to three of the followinggroups: halogen, C₁ -C₆ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₆ -alkoxy, C₁-C₄ -haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄ -alkyl, C₃ -C₈ -cycloalkyl, C₂-C₈ -alkenyl, phenyl, 1-naphthyl or 2-naphthyl, or C₁ -C₁₀ -alkyl whichis substituted by phenyl, 1-naphthyl or 2-naphthyl, where these aromaticradicals in turn may carry from one to five halogen atoms and from oneto three of the following groups: C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁-C₄ -alkoxy, C₁ -C₄ -haloalkyl or C₁ -C₄ -alkylthio, with the provisothat at least one of X or Y is selected from the group consisting of2-thienyl, 5-isoxazolyl, 4,5-dichloro-1-imidazolyl,1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2-yl and1,3,4-triazol-1-yl, which may carry from one to three of the followinggroups: halogen, C₁ -C₆ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₆ -alkoxy, C₁-C₄ -haloalkoxy, C₁ -C₃ -alkoxy, C₁ -C₄ -alkyl, C₃ -C₈ -cycloalkyl, C₂-C₈ -alkenyl, phenyl, 1-naphthyl or 2-naphthyl or C₁ -C₁₀ -alkyl whichis substituted by phenyl, 1-naphthyl or 2-naphthyl, where these aromaticradicals in turn may carry from 1 to 5 halogen atoms and from 1 to 3 ofthe following groups: C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy,C₁ -C₄ -haloalkoxy or C₁ -C₄ -alkylthio,or is 5-isoxazolyl or5-isoxazolyl substituted by from one to three of the following groups:halogen, C₁ -C₆ -alkyl, C₁ -C₅ -halo-alkyl, C₁ -C₆ -alkoxy, C₁ -C₄-haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄ -alkyl, C₃ -C₈ -cycloalkyl, C₂ -C₈-alkenyl, or C₁ -C₁₀ -alkyl which is substituted by phenyl, 1-naphthylor 2-naphthyl, where these aromatic radicals in turn may carry from oneto five halogen atoms and from one to three of the following groups: C₁-C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl or C₁-C₄ -alkylthio.
 2. A compound of the formula I as defined in claim 1,wherein X is 4,5-dichloro-1-imidazolyl.
 3. A compound of the formula Ias defined in claim 1, wherein X is 3-cyclopropyl-5-isoxazolyl.
 4. Acompound of the formula I as defined in claim 1, wherein X is3-(1-methylethyl)-5-isoxazolyl.
 5. A compound of the formula I asdefined in claim 1, wherein X is 2-cyclopropyl-1,3,4-oxadiazol-2-yl. 6.A compound of the formula I as defined in claim 1, wherein X is2-methyl-1,3,4-oxadiazol-2-yl.
 7. A compound of the formula I as definedin claim 1, wherein X is 2-cyclopropyl-1,3,4-thiadiazol-2-yl.
 8. Acompound of the formula I as defined in claim 1, wherein X is2-methyl-1,3,4-thiadiazol-2-yl.
 9. A compound of the formula I asdefined in claim 1, wherein A is methylene and X is selected from thegroup consisting of 2-thienyl, 5-isoxazolyl, 1-imidazolyl,1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2-yl and1,3,4-triazol-1-yl, which may carry from one to three of the followinggroups: halogen, C₁ -C₆ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₆ -alkoxy, C₁-C₄ -haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄ -alkyl, C₃ -C₈ -cycloalkyl or C₂-C₈ -alkenyl.
 10. A compound of the formula I as defined in claim 1,wherein A and B are each methylene and X and Y are each selected fromthe group consisting of 2-thienyl, 5-isoxazolyl,4,5-dichloro-1-imdazolyl, 1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-2-yl,1,3,4-thiadiazol-2-yl and 1,3,4-triazol-1-yl, which may carry from oneto three of the following groups: halogen, C₁ -C₆ -alkyl, C₁ -C₄-haloalkyl, C₁ -C₆ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄-alkyl, C₃ -C₈ -cycloalkyl, C₂ -C₈ -alkenyl phenyl, 1-naphthyl or2-naphthyl or C₁ -C₁₀ -alkyl which is substituted by phenyl, 1-naphthylor 2-naphthyl, where these aromatic radicals in turn may carry from 1 to5 halogen atoms and from 1 to 3 of the following groups: C₁ -C₄ -alkyl,C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C.sub. 1 -C₄ -halo-alkoxy or C₁ -C₄-alkylthio.
 11. A insecticidal, arachnicidal and nematocidal compositioncontaining a hydroquinone diether of the formula I as defined in claim 1and inert additives.
 12. A compound of the formula I as defined in claim1, wherein A and B are each methylene or ethylene.
 13. A compound of theformula I as defined in claim 1, wherein at least one of A or B ismethylene.
 14. A insecticidal, arachnicidal and nematocidal compositioncontaining a hydroquinone diether of the formula I as defined in claim12 and inert additives.
 15. A insecticidal, arachnicidal and nematocidalcomposition containing a hydroquinone diether of the formula I asdefined in claim 10 and inert additives.
 16. A method for controllinginsects arachnids and nematodes, wherein an effective amount of ahydroquinone diether of the formula I ##STR105## where R¹ is hydrogen,halogen or C₁ -C₆ -alkyl,A and B are each methylene, ethylene orpropylene, where these groups may carry one or two C₁ -C₃ -alkylradicals, and X and Y are each a 5-membered heteroaromatic structureselected from the group consisting of 2-thienyl, 3-thienyl,3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 4-isothiazolyl,5-isothiazolyl, 1-pyrazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl,2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 4,5-dichloro-1-imidazolyl,2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 1,2,4-oxadiazol-5-yl,1,3,4-oxadiazol-2-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl,1,3,4-triazol-1-yl, 1,3,4-triazol-2-yl, 1,2,4-triazol-1-yl,1,2,4-triazol-3-yl and 1,2,4-triazol-5-yl, which may carry from one tothree of the following groups: halogen, C₁ -C₆ -alkyl, C₁ -C₄-haloalkyl, C₁ -C₆ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₃ -alkoxy-C₁ -C₄-alkyl, C₃ -C₈ -cycloalkyl, C₂ -C₈ -alkenyl, phenyl, 1-naphthyl or2-naphthyl or C₁ -C₁₀ -alkyl which is substituted by phenyl, 1-naphthylor 2-naphthyl, where these aromatic radicals in turn may carry from oneto five halogen atoms and from one to three of the following groups: C₁-C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl or C₁ -C₄ -alkylthio, with the proviso that at least one of X or Y is selectedfrom the group consisting of 2-thienyl, 5-isoxazolyl,4,5-dichloro-1-imidazolyl, 1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-2-yl,1,3,4-thiadiazol-2-yl and 1,3,4-triazol-1-yl, which may carry from oneto three of the following groups: halogen, C₁ -C₆ -alkyl, C₁ -C₄-haloalkyl, C₁ -C₆ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₃ -alkoxy, C₁ -C₄-alkyl, C₃ -C₈ -cycloalkyl, C₂ -C₈ -alkenyl, phenyl, 1-naphthyl or2-naphthyl or C₁ -C₁₀ -alkyl which is substituted by phenyl, 1-naphthylor 2-naphthyl, where these aromatic radicals in turn may carry from oneto five halogen atoms and from one to three of the following gruops: C₁-C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy or C₁-C₄ -alkylthio, is allowed to act on the insects, arachnids andnematodes and/or their habitat.
 17. A method for controlling insects,arachnids and nematodes, wherein an effective amount of a hydroquinonediether of the formula I as defined in claim 12 is allowed to act on theinsects, arachnids and nematodes and/or their habitat.
 18. A method forcontrolling insects, arachnids and nematodes, wherein an effectiveamount of a hydroquinone diether of the formula I as defined in claim 13is allowed to act on the insects, arachnids and nematodes and/or theirhabitat.
 19. A method for controlling insects, arachnids and nematodes,wherein an effective amount of a hydroquinone diether of the formula Ias defined in claim 9 is allowed to act on the insects, arachnids andnematodes and/or their habitat.
 20. A method for controlling insects,arachnids and nematodes, wherein an effective amount of a hydroquinonediether of the formula I as defined in claim 10 is allowed to act on thepests and/or their habitat.